From GameBrew - a wiki dedicated to Video Game Homebrew.
Port of DeSmuME DS Emulator for the Vita.
It's currently a fully interpreted DS emulator, which means the performance is not so great.
v0.2 - Sound and Homebrew support
This version has SOUND support and you can now launch DS homebrews.
I've also added some configurations that can be changed from the menu.
ROMS MUST BE PLACED IN ux0:/data/desmume/
V0.01 - First numbered release
I decided that this should be the first numbered release since it's now a functional emulator.
JIT is now implemented (thanks to xerpi)
You can now select which rom you want to launch (albeit roms must be placed inside ux0:/data/desmume)
Launching a rom with the cross (X) button will launch the game with JIT enabled.
Launching a rom with the square ([ ]) button will launch the game with JIT disabled.
During gameplay you can press Select + Down + Left Trigger + Right Trigger to close the emulator.